Rhabdomyolysis is not just a laboratory diagnosis—it is a clinical problem that develops in the field, often in patients exposed to heat, exertion, or crush injury. In high-acuity, low-resource environments, clinicians must recognize early warning signs and act before confirmatory data is available. This lecture focuses on the practical recognition, pathophysiology, and management of rhabdomyolysis in real-world settings, emphasizing early fluid resuscitation, complication prevention, and transport decision-making. The goal is simple: identify the problem early, intervene aggressively, and prevent the downstream complications that actually kill these patients.