DevSecOps is crucial for Digital Transformation as software has become an essential component for every organization and resilient space capabilities. As software systems become more complex, ensuring their security and reliability becomes more challenging. Automation and DevSecOps methodologies help organizations to enhance the security of their software supply chain and reduce the time taken to resolve security issues/bugs through automation, resulting in improved efficiency and agility while removing error-prone human-driven processes. Automation and agile practices are being adopted by nation states, companies, and programs leading in digital transformation for maximum impact. The talk explores how Digital Engineering and DevSecOps combined yield real mission impact and how this is achievable through existing research and development completed by the Air Force RogueONE group, focusing on Digital Transformation, Digital Twins, and Digital Engineering for air and space capabilities.