Multithread (and distributed) programming is hard to design and to code, but don't worry !!!
AKKA.NET's Actor Model implementation provides all you needs to build complex multithread applications and distributed systems and with feature like resilience to crashes, remoting, clustering and more, this 'ecosystem' has no rivals.
From theory to practice, the field experience in the development of a whole application, will allow you to know the 'best practices' to be operational and to find hidden pitfalls before they happen.