A service mesh enhances the security, reliability, and observability of microservices communication. By examining Istio's Service Mesh and its use of the Gateway API for edge load balancing, we can see how it manages traffic through Envoy proxies and supports layer 4-6 load balancing. While these features offer robust traffic management, they can place significant demands on server resources. To address this, we explore the deployment of Istio Service Mesh on power- and cost-efficient ARM N2 cores, focusing on performance metrics. Leveraging these cores allows for effective handling of network and compute-intensive tasks, significantly reducing power consumption and costs. We will present data demonstrating how these strategies enhance cluster efficiency and performance, meeting the demands of next-generation cloud-native environments.