Sixtine started her career at Galerie Jan Krugier in Geneva, Switzerland where she spent on and off about 10 years finally managing the gallery in 2003. She has also served as a project manager for the Australia Council in Darwin, NT where she developed a passion for indigenous art. Upon returning from Australia she served as an Art Advisor for a private bank in Geneva. Then, she spent a decade as Director of international art and jewellery fairs throughout Europe. Taking her vast knowledge of the art world, she authored an MBA in art management for Geneva Business School in 2022 and continues to lecture at the Pons Business School of Madrid. She is currently the Art Director of WISe.ART, a multi blockchain art marketplace powered by WISeKEY specialising in cybersecurity for 25 years.